Environmentally induced epigenetic plasticity in the human parasite Schistosoma mansoni

Céline Cosseau (1) , Julie M J Lepesant (1) , David Roquis (1) , Nathalie Arancibia (1) , Christoph Grunau (1)

1 2EI - Ecologie et évolution des interactions [2011-2014]

Schistosoma mansoni is a platyhelminth parasite that uses the mollusc Biomphalaria as intermediate host and rodents or human as definitive host. We exposed S. mansoni populations to a stressful but ecological realistic environment: the interaction with an allopatric B. glabrata host in which the parasite develops into human-infecting cercaria. We then studied phenotypic traits, epigenetic and transcriptionnal changes that the parasite engages in response to this stressful environment

Domaines: Evolution [q-bio.PE]

Céline Cosseau, Julie M J Lepesant, David Roquis, Nathalie Arancibia, Christoph Grunau. Environmentally induced epigenetic plasticity in the human parasite Schistosoma mansoni. Conférences Jacques Monod « Les maladies infectieuses comme moteur de l’évolution : les défis à venir », Sep 2014, Roscoff, France. . ⟨hal-01134476⟩