Proteome evolution of deep-sea hydrothermal vent alvinellid polychaetes supports the ancestry of thermophily and subsequent adaptation to cold in some lineages

Abstract : Temperature, perhaps more than any other environmental factor, is likely to influence the evolution of all organisms. It is also a very interesting factor to understand how genomes are shaped by selection over evolutionary timescales, as it potentially affects the whole genome. Among thermophilic prokaryotes, temperature affects both codon usage and protein composition to increase the stability of the transcriptional/translational machinery, and the resulting proteins need to be functional at high temperatures. Among eu-karyotes less is known about genome evolution, and the tube-dwelling worms of the family Alvinellidae represent an excellent opportunity to test hypotheses about the emergence of thermophily in ectothermic metazoans. The Alvinellidae are a group of worms that experience varying thermal regimes, presumably having evolved into these niches over evolutionary times. Here we analyzed 423 putative orthologous loci derived from 6 alvinellid species including the thermophilic Alvinella pompejana and Paralvinella sulfincola. This comparative approach allowed us to assess amino acid composition, codon usage, divergence, direction of residue changes and the strength of selection along the alvinellid phylogeny, and to design a new eukaryotic thermophilic criterion based on significant differences in the residue composition of proteins. Contrary to expectations, the alvinellid ancestor of all present-day species seems to have been thermophilic, a trait subsequently maintained by purifying selection in lineages that still inhabit higher temperature environments. In contrast, lineages currently living in colder habitats likely evolved under selective relaxation, with some degree of positive selection for low-temperature adaptation at the protein level.
Type de document :
Article dans une revue
Genome Biology and Evolution, Society for Molecular Biology and Evolution, 2017, 9 (2), pp.279-296. 〈10.1093/gbe/evw298〉
Liste complète des métadonnées

http://hal.upmc.fr/hal-01504586
Contributeur : Gestionnaire Hal-Upmc <>
Soumis le : lundi 10 avril 2017 - 13:00:54
Dernière modification le : lundi 29 mai 2017 - 15:09:42
Document(s) archivé(s) le : mardi 11 juillet 2017 - 12:44:55

Fichier

evw298.pdf
Publication financée par une institution

Licence


Distributed under a Creative Commons Paternité 4.0 International License

Identifiants

Collections

Citation

Eric Fontanillas, Oxana V. Galzitskaya, Odile Lecompte, Mikhail Y. Lobanov, Arnaud Tanguy, et al.. Proteome evolution of deep-sea hydrothermal vent alvinellid polychaetes supports the ancestry of thermophily and subsequent adaptation to cold in some lineages. Genome Biology and Evolution, Society for Molecular Biology and Evolution, 2017, 9 (2), pp.279-296. 〈10.1093/gbe/evw298〉. 〈hal-01504586〉

Partager

Métriques

Consultations de la notice

146

Téléchargements de fichiers

18