Thoracic Outlet Syndrome: Fingertip Cannot Replace Forearm Photoplethysmography in the Evaluation of Positional Venous Outflow Impairments

Jeanne Hersant (1, 2) , Pierre Ramondou (1, 2) , Sylvain Durand (3) , Mathieu Feuilloy (4, 5) , Mickael Daligault (1) , Pierre Abraham (1, 2) , Samir Henni (1, 2)

1 CHU Angers - Centre Hospitalier Universitaire d'Angers
2 MITOVASC - MitoVasc - Physiopathologie Cardiovasculaire et Mitochondriale
3 MIP - Motricité, interactions, performance EA 4334 / Movement - Interactions - Performance
4 GSII - ESEO-GSII
5 LAUM - Laboratoire d'Acoustique de l'Université du Mans

Objective: Fingertip photoplethysmography (PPG) resulting from high-pass filtered raw PPG signal is often used to record arterial pulse changes in patients with suspected thoracic outlet syndrome (TOS). Results from venous (low-pass filtered raw signal) forearm PPG (V-PPG) during the Candlestick-Prayer (Ca + Pra) maneuver were recently classified into four different patterns in patients with suspected TOS, two of which are suggestive of the presence of outflow impairment. We aimed to test the effect of probe position (fingertip vs. forearm) and of red ( R ) vs. infrared ( IR ) light wavelength on V-PPG classification and compared pattern classifications with the results of ultrasound (US). Methods: In patients with suspected TOS, we routinely performed US imaging (US + being the presence of a positional compression) and Ca + Pra tests with forearm V-PPG IR . We recruited patients for a Ca + Pra maneuver with the simultaneous fingertip and forearm V-PPG R . The correlation of each V-PPG recording to each of the published pattern profiles was calculated. Each record was classified according to the patterns for which the coefficient of correlation was the highest. Cohen’s kappa test was used to determine the reliability of classification among forearm V-PPG IR , fingertip V-PPG R , and forearm V-PPG R . Results: We obtained 40 measurements from 20 patients (40.2 ± 11.3 years old, 11 males). We found 13 limbs with US + results, while V-PPG suggested the presence of venous outflow impairment in 27 and 20 limbs with forearm V-PPG IR and forearm V-PPG R , respectively. Fingertip V-PPG R provided no patterns suggesting outflow impairment. Conclusion: We found more V-PPG patterns suggesting venous outflow impairment than US + results. Probe position is essential if aiming to perform upper-limb V-PPG during the Ca + Pra maneuver in patients with suspected TOS. V-PPG during the Ca + Pra maneuver is of low cost and easy and provides reliable, recordable, and objective evidence of forearm swelling. It should be performed on the forearm (close to the elbow) with either PPG R or PPG IR but not at the fingertip level.

Mots clés: fingertip; forearm; movement (MeSH); pathophysiology; photoplethysmography (PPG); thoracic outlet syndrome (TOS); veins

Domaines: Sciences du Vivant [q-bio]; Sciences de l'ingénieur [physics]

Jeanne Hersant, Pierre Ramondou, Sylvain Durand, Mathieu Feuilloy, Mickael Daligault, et al.. Thoracic Outlet Syndrome: Fingertip Cannot Replace Forearm Photoplethysmography in the Evaluation of Positional Venous Outflow Impairments. Frontiers in Physiology, 2021, 12, ⟨10.3389/fphys.2021.765174⟩. ⟨hal-03582477⟩