Synthesis of novel guttiferone A derivatives: In-vitro evaluation toward Plasmodium falciparum, Trypanosoma brucei and Leishmania donovani

Yann Fromentin (1, 2, 3) , Nicolas Gaboriaud-Kolar (1, 2, 3) , Bruno Ndjakou Lenta , Jean Duplex Wansi , Didier Buisson (4) , Elisabeth Mouray (4) , Philippe Grellier (4) , Philippe Loiseau , Marie-Christine Lallemand (1, 2, 3) , Sylvie Michel (5)

1 UMR 8638 - Equipe Pharmacognosie
2 UPD5 - Université Paris Descartes - Paris 5
3 USPC - Université Sorbonne Paris Cité
4 MCAM - Molécules de Communication et Adaptation des Micro-organismes
5 COMETE - UMR 8638 - Chimie Organique, Médicinale et Extractive et Toxicologie Expérimentale

Domains: Chemical Sciences; Life Sciences [q-bio]; Microbiology and Parasitology

Yann Fromentin, Nicolas Gaboriaud-Kolar, Bruno Ndjakou Lenta, Jean Duplex Wansi, Didier Buisson, et al.. Synthesis of novel guttiferone A derivatives: In-vitro evaluation toward Plasmodium falciparum, Trypanosoma brucei and Leishmania donovani. European Journal of Medicinal Chemistry, 2013, 65, pp.284-294. ⟨10.1016/j.ejmech.2013.04.066⟩. ⟨mnhn-02070061⟩