Replacement of the 4′-Hydroxy Group of Amodiaquine and Amopyroquine by Aromatic and Aliphatic Substituents: Synthesis and Antimalarial Activity

E Paunescu , Sophie Susplugas (1) , E Boll , R Varga , Elisabeth Mouray (1) , I Grosu , Philippe Grellier (1) , Patricia Melnyk

1 MCAM - Molécules de Communication et Adaptation des Micro-organismes

Domains: Chemical Sciences; Life Sciences [q-bio]; Life Sciences [q-bio]; Microbiology and Parasitology

E Paunescu, Sophie Susplugas, E Boll, R Varga, Elisabeth Mouray, et al.. Replacement of the 4′-Hydroxy Group of Amodiaquine and Amopyroquine by Aromatic and Aliphatic Substituents: Synthesis and Antimalarial Activity. ChemMedChem, 2009, 4 (4), pp.549-561. ⟨10.1002/cmdc.200800318⟩. ⟨mnhn-02070078⟩