Pharmacomodulation on the 3-acetylursolic acid skeleton: Design, synthesis, and biological evaluation of novel N-{3-[4-(3-aminopropyl)piperazinyl]propyl}-3-O-acetylursolamide derivatives as antimalarial agents

S Gnoatto , Sophie Susplugas (1) , L Dalla Vechia , T B Ferreira , Alexandra Dassonville-Klimpt , K R Zimmer , C Demailly , Sophie da Nascimento , J Guillon , Philippe Grellier (1) , H Verli , G Gosmann , Pascal Sonnet

1 MCAM - Molécules de Communication et Adaptation des Micro-organismes

Domains: Chemical Sciences; Life Sciences [q-bio]; Microbiology and Parasitology

S Gnoatto, Sophie Susplugas, L Dalla Vechia, T B Ferreira, Alexandra Dassonville-Klimpt, et al.. Pharmacomodulation on the 3-acetylursolic acid skeleton: Design, synthesis, and biological evaluation of novel N-{3-[4-(3-aminopropyl)piperazinyl]propyl}-3-O-acetylursolamide derivatives as antimalarial agents. Bioorganic and Medicinal Chemistry, 2008, 16 (2), pp.771-782. ⟨10.1016/j.bmc.2007.10.031⟩. ⟨mnhn-02070093⟩