Q. Qiao, S. Le-manach, H. Huet, E. Duvernois-berthet, S. Chaouch et al., , p.533

B. Sotton, L. Ponger, A. Marie, L. Mathéron, S. Lennon et al., , p.534

C. Bernard, C. Edery, M. Marie, and B. , An integrated omic analysis of 535 hepatic alteration in medaka fish chronically exposed to cyanotoxins with 536 possible mechanisms of reproductive toxicity, Environ. Pollut, vol.219, pp.119-131, 2016.

Q. Qiao, S. Le-manach, B. Sotton, H. Huet, and E. Duvernois-berthet, , p.539

C. Ponger, L. Marie, A. Blond, A. Mathéron, L. Vinh et al., , p.540

C. Bernard, C. Edery, M. Marie, and B. , Deep sexual dimorphism in adult 541 medaka fish liver highlighted by multi-omic approach, Sci. Rep, vol.6, 2016.

Q. Qiao, W. Liu, K. Wu, T. Song, J. Hu et al., Female zebrafish (Danio rerio) are more vulnerable than males to 545 microcystin-LR exposure, without exhibiting estrogenic effects, Aquat. Toxicol, vol.544, pp.272-282, 2013.

S. Shenolikar, Protein serine/threonine phosphatases -new avenues for cell 548 regulation, Annu. Biol, vol.10, pp.55-86, 1994.

A. Singo, J. G. Myburgh, P. N. Laver, E. A. Venter, C. H. Gezina et al., , p.550

C. J. Botha, Vertical transmission of microcystins to Nile crocodile 551 (Crcocodylus niloticus) eggs, Toxicon, vol.134, pp.50-56, 2017.

L. Spoof and A. Catherine, Appendix 3: Tables of microcystins and nodularins, in: 554 Handbook of Cyanobacterial Monitoring and Cyanotoxin Analysis, vol.555, pp.526-537, 2017.

K. Steiner, B. Hagenbuch, and D. R. Dietrich, Molecular cloning and functional 557 characterization of a rainbow trout liver Oatp, Toxicol. Appl. Pharmacol, vol.280, pp.558-534, 2014.

K. Steiner, L. Zimmermann, B. Hagenbuch, and D. Dietrich, Zebrafish, vol.560, 2016.

, Oatp-mediated transport of microcystin congeners, Arch. Toxicol, vol.90, pp.1129-1139

Y. Su, L. Li, J. Hou, N. Wu, W. Lin et al., Life-cycle exposure to 563 microcystin-LR interferes with the reproductive endocrine system of male 564 zebrafish, Aquat. Toxicol, vol.175, pp.205-212, 2016.

E. Testai, F. M. Buratti, E. Funari, M. Manganelli, S. Vichi et al., , p.566

V. Fessard and A. Sialehaamoa, Review and analysis of occurrence , 567 exposure and toxicity of cyanobacteria toxins in food, 2016.

I. Trinchet, S. Cadel-six, C. Djediat, B. Marie, C. Bernard et al., , p.570

S. Edery and M. , Toxicity of harmful cyanobacterial blooms to bream and 571 roach, Toxicon, vol.71, pp.121-127, 2013.

H. T. Wan, D. D. Mruk, C. K. Wong, and C. Y. Cheng, The apical ES-BTB-BM 573 functional axis is an emerging target for toxicant-induced infertility, Trends Mol, 2013.

. Med, , vol.19, pp.396-405

L. Wang, X. Wang, Z. Geng, Y. Zhou, Y. Chen et al., , 2013.

, Ecotoxicology, vol.22, pp.1555-1563

X. Wang, Y. Chen, X. Zuo, N. Ding, H. Zeng et al., Microcystin 579 (-LR) induced testicular cell apoptosis via up-regulating apoptosis-related genes 580 in vivo, Food Chem. Toxicol, vol.60, pp.309-317, 2013.

T. Yoshida, Y. Makita, T. Tsutsumi, S. Nagata, F. Tashiro et al., , p.582

M. Tamura, S. Harada, T. Maita, K. Ueno, and Y. , Immunohistochemical 583 localization of microcystin-LR in the liver of mice: A study on the pathogenesis 584 of microcystin-LR-induced hepatotoxicity, Toxicol. Pathol, vol.26, pp.411-418, 1998.

T. Yoshida, T. Tsutsumi, S. Nagata, F. Yoshida, K. Maita et al., Quantitative analysis of intralobular distribution of microcystin-LR in the 588 mouse liver, J. Toxicol. Pathol, vol.14, pp.205-212, 2001.

A. Zeck, A. Eikenberg, M. G. Weller, and R. Niessner, Highly sensitive 590 immunoassay based on a monoclonal antibody specific for [ 4-arginine ] 591 microcystins, Anal. Chim. Acta, vol.441, pp.1-13, 2001.

H. Zhang, C. Cai, W. Fang, J. Wang, Y. Zhang et al., Oxidative 593 damage and apoptosis induced by microcystin-LR in the liver of Rana 594 nigromaculata in vivo, Aquat. Toxicol, pp.140-141, 2013.

S. Zhao, P. Xie, G. Li, C. Jun, Y. Cai et al., The proteomic 597 study on cellular responses of the testes of zebrafish (Danio rerio) exposed to 598 microcystin-RR, Proteomics, vol.12, pp.300-312, 2012.

M. Zhou, W. W. Tu, and J. Xu, Mechanisms of microcystin-LR-induced 600 cytoskeletal disruption in animal cells, Toxicon, vol.101, pp.92-100, 2015.

Y. Zhou, Y. Chen, M. Yuan, Z. Xiang, and X. Han, In vivo study on the effects 603 of microcystin-LR on the apoptosis, proliferation and differentiation of rat 604 testicular spermatogenic cells of male rats injected i.p. with toxins, J. Toxicol, 2013.

. Sci, , vol.38, pp.661-70

Y. Zhou, J. Yuan, J. Wu, and X. Han, The toxic effects of microcystin-LR on rat 607 spermatogonia in vitro, Toxicol. Lett, vol.212, pp.48-56, 2012.