Specificity of the metabolic signatures of fish from cyanobacteria rich lakes

Abstract : The liver metabolomes of fish from cyanobacterial-dominated ponds were investigated. Cyanobacterial metabolites were only be detected in cyanobacterial dominated ponds. The metabolomes of the 2 fish species exhibit similar correlation with cyanobacteria occurrence. Correlations between the levels of some metabolites and phycocyanin or pH were observed. a b s t r a c t With the increasing impact of the global warming, occurrences of cyanobacterial blooms in aquatic ecosystems are becoming a main worldwide ecological concern. Due to their capacity to produce potential toxic metabolites, interactions between the cyanobacteria, their cyanotoxins and the surrounding freshwater organisms have been investigated during the last past years. Non-targeted metabolomic analyses have the powerful capacity to study simultaneously a high number of metabolites and thus to investigate in depth the molecular signatures between various organisms encountering different environmental scenario, and potentially facing cyanobacterial blooms. In this way, the liver metabolomes of two fish species (Perca fluviatilis and Lepomis gibbosus) colonizing various peri-urban lakes of theÎle-de-France region displaying high biomass of cyanobacteria, or not, were investigated. The fish metabolome hydrophilic fraction was analyzed by 1 H NMR analysis coupled with Batman peak treatment for the quantification and the annotation attempt of the metabolites. The results suggest that similar metabolome profiles occur in both fish species, for individuals collected from cyanobacterial blooming lakes compared to organism from non-cyanobacterial dominant environments. Overall, such environmental metabolomic pilot study provides new research perspectives in ecology and ecotoxicology fields, and may notably provide new information concerning the cyanobacteria/fish eco-toxicological interactions.
Document type :
Journal articles
Complete list of metadatas

Cited literature [42 references]  Display  Hide  Download

https://hal-mnhn.archives-ouvertes.fr/mnhn-02299394
Contributor : Charlotte Duval <>
Submitted on : Monday, September 30, 2019 - 12:05:59 PM
Last modification on : Tuesday, October 29, 2019 - 4:10:47 PM

File

Sotton et al 2019.pdf
Files produced by the author(s)

Identifiers

Collections

Citation

Benoît Sotton, Alain Paris, Séverine Le Manach, Alain Blond, Charlotte Duval, et al.. Specificity of the metabolic signatures of fish from cyanobacteria rich lakes. Chemosphere, Elsevier, 2019, 226, pp.183-191. ⟨10.1016/j.chemosphere.2019.03.115⟩. ⟨mnhn-02299394⟩

Share

Metrics

Record views

33

Files downloads

17