New Benthic Cyanobacteria from Guadeloupe Mangroves as Producers of Antimicrobials

Sébastien Duperron (1, 2) , Mehdi A Beniddir (3) , Sylvain Durand (1) , Arlette Longeon (1) , Charlotte Duval (1) , Olivier Gros (4, 5) , Cécile Bernard (1) , Marie-Lise Bourguet-Kondracki (1)

1 MCAM - Molécules de Communication et Adaptation des Micro-organismes
2 IUF - Institut universitaire de France
3 BioCIS - Biomolécules : Conception, Isolement, Synthèse
4 Université des Antilles (Pôle Guadeloupe)
5 ISYEB - Institut de Systématique, Evolution, Biodiversité

Benthic cyanobacteria strains from Guadeloupe have been investigated for the first time by combining phylogenetic, chemical and biological studies in order to better understand the taxonomic and chemical diversity as well as the biological activities of these cyanobacteria through the effect of their specialized metabolites. Therefore, in addition to the construction of the phylogenetic tree, indicating the presence of 12 potentially new species, an LC-MS/MS data analysis workflow was applied to provide an overview on chemical diversity of 20 cyanobacterial extracts, which was linked to antimicrobial activities evaluation against human pathogenic and ichtyopathogenic environmental strains.

Mots clés: tropical mangrove; benthic cyanobacteria; Guadeloupe; phylogenetic diversity; molecular networking; chemical diversity; antimicrobial activity

Domaines: Ecologie, Environnement; Biochimie, Biologie Moléculaire; Biologie moléculaire; Chimie

Sébastien Duperron, Mehdi A Beniddir, Sylvain Durand, Arlette Longeon, Charlotte Duval, et al.. New Benthic Cyanobacteria from Guadeloupe Mangroves as Producers of Antimicrobials. Marine drugs, 2020, ⟨10.3390/md18010016⟩. ⟨mnhn-02423405⟩