Synthesis of an organo-ruthenium aminoquinoline-trioxane hybrid and evaluation of its activity against Plasmodium falciparum and its toxicity toward normal mammalian cells

Alberto Martínez , Christiane Deregnaucourt (1) , Veronique Sinou (2) , Christine Latour (2) , Dipankar Roy (3) , Joseph Schrével (4) , Roberto Sánchez-Delgado (5)

1 MCAM - Molécules de Communication et Adaptation des Micro-Organismes
2 IP-TPT - Infections Parasitaires : Transmission, Physiopathologie et Thérapeutiques
3 Chemistry Department of Brooklyn College and Ph.D. Program in Chemistry
4 MCAM - Molécules de Communication et Adaptation des Micro-organismes
5 Chemistry Department

Domains: Chemical Sciences; Microbiology and Parasitology

Alberto Martínez, Christiane Deregnaucourt, Veronique Sinou, Christine Latour, Dipankar Roy, et al.. Synthesis of an organo-ruthenium aminoquinoline-trioxane hybrid and evaluation of its activity against Plasmodium falciparum and its toxicity toward normal mammalian cells. Medicinal Chemistry Research, 2017, 26 (2), pp.473-483. ⟨10.1007/s00044-016-1769-6⟩. ⟨mnhn-02878030⟩