Evolutionary demographic models reveal the strength of purifying selection on susceptibility alleles to late-onset diseases

Samuel Pavard (1) , Christophe Coste (1, 2)

1 EA - Éco-Anthropologie
2 Department of Biology, Centre for Biodiversity Dynamics, Norwegian University of Science and Technology, Trondheim, Norway

Domaines: Biodiversité et Ecologie; Génétique; Sciences de l'Homme et Société

Samuel Pavard, Christophe Coste. Evolutionary demographic models reveal the strength of purifying selection on susceptibility alleles to late-onset diseases. Nature Ecology & Evolution, 2021, 5 (3), pp.392-400. ⟨10.1038/s41559-020-01355-2⟩. ⟨mnhn-03252945⟩