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Using micro computed tomographic imaging for analyzing kidney stones

Abstract : Stone analysis is a critical part of the clinical characterization of urolithiasis. This article reviews the strengths and limitations of micro CT in the analysis of stones. Using micro CT alone in a series of 757 stone specimens, micro CT identified the 458 majority calcium oxalate specimens with a sensitivity of 99.6% and specificity of 95.3%. Micro CT alone was also successful in identifying majority apatite, brushite, uric acid, and struvite stones. For some minor minerals-such as apatite in calcium oxalate or calcium salts in uric acid stones-micro CT enables the detection of minute quantities well below 1%. The addition of a standard for calibrating X-ray attenuation values improves the ability of micro CT to identify common stone minerals. The three-dimensional nature of micro CT also allows for the visualization of surface features in stones, which is valuable for the study of stone formation.
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https://hal.sorbonne-universite.fr/hal-03335928
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Submitted on : Monday, September 6, 2021 - 4:02:08 PM
Last modification on : Wednesday, January 26, 2022 - 4:45:33 PM
Long-term archiving on: : Tuesday, December 7, 2021 - 7:10:27 PM

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CRCHIM_2021__24_S2_A4_0.pdf
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James Williams, James Lingeman, Michel Daudon, Dominique Bazin. Using micro computed tomographic imaging for analyzing kidney stones. Comptes Rendus. Chimie, Académie des sciences (Paris), 2021, 24 (S2), pp.1-12. ⟨10.5802/crchim.89⟩. ⟨hal-03335928⟩

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