A Facile and High Yielding Synthesis of Symmetrical and Unsymmetrical Diarylalkynes Using Diethyl Dichloromethylphosphonate as Precursor

Virginie Mouriès (1) , Rachel Waschbüsch (1) , John Carran (1) , Philippe Savignac (1)

1 DCPH - Laboratoire Hétéroéléments et Coordination

The reaction, under internal quench conditions, of diethyl dichloromethylphosphonate and symmetrical or unsymmetrical diarylketones in the presence of n-BuLi, leads to the corresponding symmetrical or unsymmetrical diarylalkynes via a Fritsch-Buttenberg-Wiechell rearrangement in a simple, high yielding, onepot reaction.

Domaines: Chimie organique

Virginie Mouriès, Rachel Waschbüsch, John Carran, Philippe Savignac. A Facile and High Yielding Synthesis of Symmetrical and Unsymmetrical Diarylalkynes Using Diethyl Dichloromethylphosphonate as Precursor. Synthesis: Journal of Synthetic Organic Chemistry, 1998, 1998 (3), pp.271-274. ⟨10.1055/s-1998-2037⟩. ⟨hal-03166314⟩