Synthesis and in Vitro and in Vivo Antimalarial Activity of N 1 -(7-Chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine Derivatives

Adina Ryckebusch (1) , Rebecca Déprez-Poulain (2) , Louis Maes (3) , Marie-Ange Debreu-Fontaine , Elisabeth Mouray (4) , Philippe Grellier (4) , Christian Sergheraert (5)

1 IBLI - Institut de biologie de Lille - IBL
2 Biostructures et Decouverte de Medicament
3 LMPH - Laboratory of Microbiology, Parasitology and Hygiene [Antwerpen]
4 MCAM - Molécules de Communication et Adaptation des Micro-organismes
5 Université de Lille, Droit et Santé

Domaines: Microbiologie et Parasitologie; Chimie

Adina Ryckebusch, Rebecca Déprez-Poulain, Louis Maes, Marie-Ange Debreu-Fontaine, Elisabeth Mouray, et al.. Synthesis and in Vitro and in Vivo Antimalarial Activity of N 1 -(7-Chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine Derivatives. Journal of Medicinal Chemistry, 2003, 46 (4), pp.542-557. ⟨10.1021/jm020960r⟩. ⟨mnhn-02867486⟩